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折扣/货期| 货号：CDX-M0065-M100 | 规格：100 mg | 目录价：￥3682 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TSQ
别名:
N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide; N-(6-Methoxy-8-quinolinyl)-4-methylbenzenesulfonamide; NSC 120213
产品描述:
TSQ (N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide) is a highly sensitive, membrane-permeable fluorescent probe widely used for the selective detection and imaging of intracellular zinc (Zn2+) ions. It is selective for Zn (II) in the presence of physiological concentrations of Ca (II) and Mg (II) ions. Upon binding to Zn2+, TSQ exhibits a strong blue fluorescence, making it a powerful tool in cellular and neurobiological studies involving zinc homeostasis, signaling, and transport. It is hypothesized that Zn-TSQ fluorescence, blue-shifted from the 490 nm emission maximum of Zn(TSQ)2, results from ternary complex, TSQ-Zn-protein formation. A study showed that TSQ-zinc complex formed in pancreatic tumors induced cell death if zinc is overloaded. TSQ is commonly applied in fluorescence microscopy and flow cytometry to visualize labile zinc pools in live cells and tissues. Spectral Data: lambdaEx=360nm; lambdaEm=490nm.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
328.39
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
109628-27-5
分子式:
C17H16N2O3S
促销活动
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