Ulipristal acetate-其他小分子化合物-深圳欣博盛生物科技有限公司

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Ulipristal acetate

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-U0027-M050	规格：50 mg	目录价：￥2310
货号：CDX-U0027-M100	规格：100 mg	目录价：￥3864

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Ulipristal acetate

别名:

(11beta)-17-(Acetyloxy)-11-[4-(dimethylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione; CDB-2914; HRP 2000; RU 44675

产品描述:

Ulipristal acetate is a selective progesterone receptor modulator (SPRM) that binds to the human progesterone receptors PR-A and PR-B (EC50s=8.5 and 7.7nM, respectively), rabbit uterine PR (EC50=13.6nM), and rabbit thymic glucocorticoid receptor (GR; EC50=15.4nM). It is selective for human progesterone receptors over the human estrogen receptor (ER; EC50>10,000nM). It inhibits growth of IGROV-1 and SKOV3 human ovarian cancer cells (IC50s=15.5 and 31.5µM, respectively) even after resistance to combined cisplatin and paclitaxel treatment has developed. Ulipristal acetate reverses the proliferative effect of progesterone on patient-derived germline mutant BRCA1 breast tissue xenografts in ovariectomized athymic mice. Formulations containing ulipristal acetate have been used as emergency contraceptives and to treat uterine fibroids.

宿主来源:

Synthetic

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

475.62

产品形式:

solid

产地:

瑞士