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折扣/货期| 货号：SYN-1211-M001 | 规格：1 mg | 目录价：￥1512 |
| 货号：SYN-1211-M005 | 规格：5 mg | 目录价：￥2716 |
| 货号：SYN-1211-M010 | 规格：10 mg | 目录价：￥4228 |
| 货号：SYN-1211-M050 | 规格：50 mg | 目录价：￥14364 |
| 货号：SYN-1211-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
URMC-099
别名:
3-(1H-Indol-5-yl)-5-(4-(4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3- b]pyridine
产品描述:
Inhibition of mixed lineage kinase 3 (MLK-3) is a potential strategy for the treatment of Parkinson's disease and HIV-1 associated neuro-cognitive disorders (HAND), requiring an inhibitor that can achieve significant brain concentration levels. URMC-099 is an orally bioavailable MLK-3 inhibitor with excellent brain exposure in mouse PK models and minimal interference with key human CYP450 enzymes or hERG channels. URMC-099 inhibits multiple kinase pathways, including MLK-3 (14nM) and leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (11nM).
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
421.5
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
1229582-33-5
分子式:
C27H27N5
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