深圳欣博盛生物科技有限公司 a1

Ursodeoxycholic acid
货号:CDX-U0019-G005 规格:5 g 目录价:¥1596
货号:CDX-U0019-G025 规格:25 g 目录价:¥6398
产品详情
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产品名称:
Ursodeoxycholic acid
别名:
UDCA; USAN; BRN 3219888; NSC 657950; NSC 683769; 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid; 5beta-Cholan-24-oic acid-3alpha,7beta-diol; 7beta-Hydroxylithocholic acid; UDCS
产品描述:
Endogenous hydrophilic bile acid. Antioxidant. Cytoprotective against oxidative stress and cell death. Hepatoprotective at cellular and molecular level, including stabilization of membranes. Antiapoptotic and antinecrotic. Targets the mitochondrial function and integrity, reduction of endoplasmatic stress and interactions with survival signals in cAMP, Akt, NF-kappaB, MAPK and PI3K signaling pathways. Chemopreventive against colorectal cancer by countering the tumor-promoting effects of secondary bile acids. Shows also effects on epidermal growth factor receptor (EGFR) signaling and COX-2 expression. Immunomodulator and anti-inflammatory compound. Modifies TLR4 and TLR9 signaling pathways and downregulates the production of proinflammatory tumor necrosis factor-alpha (TNF-alpha). Pregnane X receptor agonist. Neuroprotective. Anticholestatic agent. Used to reduce cholesterol absorption and for cholesterol gallstone dissolution.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
392.57
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>99% (T)
CAS号:
128-13-2
分子式:
C24H40O4
溶解度:
Soluble in DMSO or ethanol.
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