VHR Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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VHR Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：91-590

规格：0.05 mg

目录价：￥8125.65

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

VHR Recombinant Protein

别名:

Dual specificity protein phosphatase 3, DUSP3, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, VHR

表达系统:

E. coli

保存温度:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

Supplied as a 0.2 um filtered solution of PBS,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

产地:

美国

生产商:

Prosci

功能与背景:

Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs are major modulators of critical signalling pathways that are dysregulated in various diseases. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. DUSP3 is expressed in human tissues including breast and ovarian.DUSP3 shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Human DUSP3 specifically dephosphorylates and inactivates ERK1 and ERK2.

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Accession #:

P51452

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