货号:AG-CN2-0424-M001 | 规格:1 mg | 目录价:¥840 |
货号:AG-CN2-0424-M005 | 规格:5 mg | 目录价:¥2520 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Wedelolactone
别名:
7-Methoxy-5,11,12-trihydroxy-coumestan; WDL
产品描述:
Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor [2]. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha [2]. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor [1, 2]. Anti-inflammatory [2]. HIV-1 integrase inhibitor [3]. Anticancer and antiproliferative compound [4, 5]. Modulates androgen receptor (AR) activation [4]. Apoptosis inducer via downregulation of PKCepsilon [5, 9]. DNA topoisomerase IIalpha inhibitor [6]. G protein-coupled receptor-35 (GPR35) agonist [7]. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway [8]. STAT1 protein dephosphorylation inhibitor [10]. Antifibrotic [11].
宿主来源:
Isolated from Eclipta prostrata.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
314.2
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
524-12-9
分子式:
C16H10O7
溶解度:
Soluble in DMSO or methanol.
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