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折扣/货期| 货号：AG-CN2-0023-M001 | 规格：1 mg | 目录价：￥480 |
| 货号：AG-CN2-0023-M005 | 规格：5 mg | 目录价：￥960 |
| 货号：AG-CN2-0023-M025 | 规格：25 mg | 目录价：￥2880 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Wortmannin
别名:
KY 12420; BRN 0067676; NSC 627609; Antibiotic SL-2052
产品描述:
Antibiotic [1]. Potent anti-neutrophil agent with cardioprotective effects [1, 13]. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations [2, 5, 14]. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K) [3, 4]. Similar potency in vitro for the class I, II, and III PI3K. Antitumor compound. [6] Radiosensitizing agent [8]. Adipogenesis inhibitor [5, 7]. Angiogenesis inhibitor. [10] Autophagy inhibitor, regardless of the nutrient status and thus is a more suitable autophagy inhibitor than 3-MA [12,18]. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor [8, 9, 14]. Potentiates the LPS-induced nitric oxide (NO) production from macrophages [11]. Induces in vivo Alzheimer-like hyperphosphorylation in tau [15]. Polo-like kinase family inhibitor [16]. TRAIL sensitizer [19]
宿主来源:
Isolated from Penicillium sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
428.4
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
19545-26-7
分子式:
C23H24O8
溶解度:
Soluble in DMSO methanol, ethanol or chloroform. Slightly soluble in water.
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