Xanthotoxol-其他小分子化合物-深圳欣博盛生物科技有限公司

首页产品中心其他小分子化合物

Xanthotoxol

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-X0023-M025

规格：25 mg

目录价：￥3416

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Xanthotoxol

别名:

8-Hydroxypsoralen

产品描述:

Xanthotoxol is a coumarin and a major component in C. monnieri that has diverse biological activities, including anti-inflammatory, antioxidant, neuroprotective or anti-proliferative properties. It inhibits proliferation of HeLa and HepG2 cells in vitro. Xanthotoxol increases histamine release from mast cells and decreases secretion of TNF-alpha, IL-4, and IL-1beta from RBL-2H3 cells induced by DNP-human serum albumin (DNP-HSA). It is nematocidal against M. incognita. Xanthotoxol reduces brain edema, neutrophil infiltration, blood-brain barrier disruption, production of IL-1beta, TNF-alpha, IL-8, and nitric oxide (NO), and levels of intercellular adhesion molecule-1 (ICAM-1) and E-selectin in a rat model of focal cerebral ischemia. Xanthotoxol promoted NSCLC cell cycle arrest and apoptosis, and inhibited EMT by suppressing the activity of PI3K-AKT pathway, thus attenuating NSCLC proliferation and metastasis. Xanthotoxol provides itch relieve in mice by suppressing spinal GRP/GRPR signaling. This compound can be used as internal analytical reference material.

宿主来源:

Synthetic

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

202.16

产品形式:

solid

产地:

瑞士