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折扣/货期| 货号：AG-CN2-0067-C500 | 规格：500 ug | 目录价：￥2880 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
10Z-Hymenialdisine
别名:
Hymenialdisine; 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
产品描述:
Insecticidal and cytotoxic [1]. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines [2, 3, 4, 9]. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1) [5, 6]. Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor [7]. MARK (microtubule affinity-regulating kinase) inhibitor [8].
宿主来源:
Isolated from sponge Axinella carteri.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
324.1
产品形式:
solid
产地:
瑞士
纯度:
>97% (HPLC) (Contains traces of the 10E-isomer)
CAS号:
82005-12-7
分子式:
C11H10BrN5O2
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