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折扣/货期| 货号：AG-CN2-0066-G001 | 规格：1 g | 目录价：￥420 |
| 货号：AG-CN2-0066-G005 | 规格：5 g | 目录价：￥1560 |
| 货号：AG-CN2-0066-G025 | 规格：25 g | 目录价：￥4680 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Gentamicin sulfate (USP Grade)
别名:
Apogen; Garamycin; Gentiomycin C; Refobacin; NSC-82261
产品描述:
Aminoglycoside antibiotic. Protein synthesis inhibitor. Causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. Antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas. Used as a selection agent (gentamicin-resistance gene) in molecular biology applications. Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies. Bactericidal effects are exerted by the binding to the outer membrane, causing disruption of the membrane. This increases the permeability of the cell envelope, leakage of cell contents, and leading to apoptosis and proteolysis (cell death). Causes also cell death by generation of free radicals, phospholipidosis, extracellular calcium-sensing receptor stimulation and energetic catastrophe.
宿主来源:
Isolated from Micromonospora sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
575.6
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
Mixture of gentamicin C1, C1a, C2, C2a and C2b.
生物活性:
Potency (dry basis) >590µg/mg
CAS号:
1405-41-0
分子式:
C21H43N5O7 . H2SO4 (unspecified)
溶解度:
Soluble in water. Almost insoluble in alcohol or ether.
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