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折扣/货期| 货号：AG-CN2-0519-C500 | 规格：500 ug | 目录价：￥3480 |
| 货号：AG-CN2-0519-M001 | 规格：1 mg | 目录价：￥5400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
4-Fluorophenylundecanoyl-alpha-galactosylceramide [7DW8-5]
别名:
7DW8-5; (2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-(11-(4-fluorophenyl)undeaconyl)-2-amino-1,3,4-octadecanetriol
产品描述:
Glycolipid derivative of alpha-GalCer. Potent stimulator of invariant natural killer T (iNKT) cells (140-fold lower EC50 compared to alpha-GalCer). Specific ligand (strongest binding affinity) of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells with. Show to induce secretion of key cytokines such as IFN-gamma and IL-12, and activate autologous dendritic cells, as well as binding to CD1d and the invariant T cell receptor (invTCR). Potent vaccine adjuvant (~100 times stronger than alpha-GalCer) that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Potential immunotherapeutic to treat cancer, infectious diseases and autoimmune diseases.
保存温度:
+4°C
运输温度:
BI
预期分子量:
742
产品形式:
solid
产地:
瑞士
纯度:
>95% (1H-NMR, 13C-NMR and TLC (CH2Cl2/MeOH 85:15)
CAS号:
n.d.
分子式:
C41H72FNO9
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