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折扣/货期| 货号：CDX-A0099-M025 | 规格：25 mg | 目录价：￥3500 |
| 货号：CDX-A0099-M050 | 规格：50 mg | 目录价：￥6132 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
9-Amino-6-chloro-2-methoxyacridine
别名:
ACMA; 2-Methoxy-6-chloro-9-aminoacridine; 9-Amino-3-chloro-7-methoxyacridine; G 185; NSC 15300
产品描述:
9-Amino-6-chloro-2-methoxyacridine (ACMA) is a cell-permeable ph-sensitive fluorescent probe that intercalates into DNA. It selectively binds to poly(dA-dT) sequences with the fluorescence lifetime decreasing with incorporation of guanosine. It is used for nucleic acid staining/labeling. ACMA fluorescence is pH-dependent and is quenched when a pH gradient is established. Spectral Data: lambdaex 411nm; lambdaem 475nm (in methanol). Excitation of the ACMA-DNA complex (excitation/emission maxima lambda419/483 nm) is possible with most UV-light sources, making it compatible for use with both shorter- and longer-wavelength dyes. ACMA also apparently binds to membranes in the energized state and becomes quenched if a pH gradient forms. It has been extensively employed to follow cation and anion movement across membranes and to study the proton-pumping activity of various membrane-bound ATPases. ACMA also inhibits acetylcholinesterase.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
258.7
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
3548-09-2
分子式:
C14H11ClN2O
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