官网链接
折扣/货期| 货号：CDX-A0692-M010 | 规格：10 mg | 目录价：￥784 |
| 货号：CDX-A0692-M050 | 规格：50 mg | 目录价：￥3150 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Apixaban
别名:
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; BMS 562247-01
产品描述:
Apixaban is an orally active, active site-targeting, highly potent and selective inhibitor of factor Xa (FXa), an essential component of the coagulation cascade. It functions by selectively binding to both free and clot-bound factor Xa, thereby inhibiting its activity and preventing the conversion of prothrombin to thrombin. This inhibition ultimately leads to the prevention of thrombin formation and subsequent blood clot formation. Apixaban achieves this by targeting the active site of factor Xa, interfering with its ability to interact with its substrates. By doing so, it effectively disrupts the coagulation process and impedes the formation of fibrin clots. This mechanism of action makes apixaban a promising candidate for research and development aimed at understanding and manipulating the coagulation cascade. In vivo, apixaban has antithrombotic efficacy in vivo in a rabbit model of venous thrombosis. Formulations containing apixaban have been used to prevent blood clot formation in patients with atrial fibrillation.
宿主来源:
Synthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
459.5
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
503612-47-3
分子式:
C25H25N5O4
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询