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折扣/货期| 货号：SYN-1230-M001 | 规格：1 mg | 目录价：￥1204 |
| 货号：SYN-1230-M005 | 规格：5 mg | 目录价：￥2268 |
| 货号：SYN-1230-M010 | 规格：10 mg | 目录价：￥3332 |
| 货号：SYN-1230-M050 | 规格：50 mg | 目录价：￥11340 |
| 货号：SYN-1230-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Alpelisib
别名:
(2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidinedicarboxamide; BYL719; NVP-BYL719
产品描述:
Selective PI3Kalpha inhibitor with IC50 of 5nM. Has minimal effect on other PI3K isoforms. Exhibits favorable pharmacokinetics and excellent oral bioavailability in animal models. In xenografts using nude mice, it showed dose-dependent effects of tumour inhibition. In a phase Ib study, it showed synergistic anti-tumor activity with endocrine therapy against ER+/PIK3CA mutated breast cancer cells.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
441.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1217486-61-7
分子式:
C19H22F3N5O2S
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