| 货号:SYN-1231-M001 | 规格:1 mg | 目录价:¥1358 |
| 货号:SYN-1231-M005 | 规格:5 mg | 目录价:¥2870 |
| 货号:SYN-1231-M010 | 规格:10 mg | 目录价:¥4382 |
| 货号:SYN-1231-M050 | 规格:50 mg | 目录价:¥13454 |
| 货号:SYN-1231-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Selonsertib (free base)
别名:
GS-4997 (free base); 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide
产品描述:
Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
445.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1448428-04-3
分子式:
C24H24FN7O
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