Amyloid Fibrils (OC) Antibody: Biotin-多抗-深圳欣博盛生物科技有限公司

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Amyloid Fibrils (OC) Antibody: Biotin

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-507D-BI

规格：100 µl

目录价：￥4699.8

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Amyloid Fibrils (OC) Antibody: Biotin

别名:

OC Antibody, Fibrils Antibody, Amyloid Oligomer aß Antibody, A11 Antibody, Amyloid beta A4 protein Antibody, ABPP Antibody, APPI Antibody, Alzheimer disease amyloid protein Antibody, Cerebral vascular amyloid peptide Antibody, PreA4 Antibody, Protease nexin-II Antibody, APP Antibody, A4 Antibody, AD Antibody

产品描述:

Rabbit Anti-Human Amyloid Fibrils (OC) Polyclonal

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB | IHC | ICC/IF | IP | ELISA | DB

靶标/特异性:

Recognizes generic epitopes common to many amyloid fibrils and fibrillar oligomers, but not prefibrillar oligomers or natively folded proteins. Expected to detect in Mouse and Rat based on species homology.

推荐稀释度:

WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Fibrils prepared from human amyloid beta 42 peptide

免疫原种属:

Human

克隆性:

Polyclonal

纯化方式:

Protein A Purified

偶联:

Biotin

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres (1, 2). These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease (2, 3).