货号:SYN-1011-M001 | 规格:1 mg | 目录价:¥1204 |
货号:SYN-1011-M005 | 规格:5 mg | 目录价:¥2268 |
货号:SYN-1011-M010 | 规格:10 mg | 目录价:¥3780 |
货号:SYN-1011-M050 | 规格:50 mg | 目录价:¥11186 |
货号:SYN-1011-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AT9283
别名:
AT-9283
产品描述:
Aurora kinases play a key role in the regulation of mitosis and in recent years have become attractive targets for the treatment of cancer. AT9283 is a powerful inhibitor of Aurora A and B kinases as well as several other important kinases including JAK2 and Abl (T315I). AT9283 has also been shown effective in mouise xenograft models and has been studied as a possible clinical candidate. Effective IC(50) doses for Aurora kinases are in the low 2-3nM range, and inhibition of a number of other kinases including JAK2 has been reported at 1-10nM.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
381.4
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
896466-04-9
分子式:
C19H23N7O2
溶解度:
Soluble in DMSO or ethanol.
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