Bassoon Antibody-多抗-深圳欣博盛生物科技有限公司

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Bassoon Antibody

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-198D

规格：100 µg

目录价：￥4246.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Bassoon Antibody

别名:

BSN Antibody, ZNF231 Antibody, Neuronal double zine finger protein Antibody

产品描述:

Rabbit Anti-Human Bassoon Polyclonal

反应种属:

Human | Mouse | Rat

宿主来源:

Rabbit

实验应用:

WB | IHC

靶标/特异性:

Detects ~420kDa. Multiple isoforms can be detected.

推荐稀释度:

WB (1:1000), IHC (1:400); optimal dilutions for assays should be determined by the user.

免疫原:

NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein of human Bassoon

免疫原种属:

Human

克隆性:

Polyclonal

纯化方式:

Protein A Purified

偶联:

Unconjugated

产品浓度:

1 mg/ml

保存温度:

-20ºC

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).

Accession #:

NP_003449.2