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折扣/货期| 货号：SYN-1225-M001 | 规格：1 mg | 目录价：￥2870 |
| 货号：SYN-1225-M005 | 规格：5 mg | 目录价：￥5894 |
| 货号：SYN-1225-M010 | 规格：10 mg | 目录价：￥9828 |
| 货号：SYN-1225-M050 | 规格：50 mg | 目录价：￥询价 |
| 货号：SYN-1225-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BBT594
别名:
BBT-594
产品描述:
BBT594 (NVP-BBT594) is a potent and selective inhibitor of RET and JAK2. BBT594 impairs "glial-derived neurotrophic factor" (GDNF)-RET signaling and GDNF-dependent growth in specific in vitro models. Direct inhibition of GDNF-RET signaling by BBT594 in ER+ breast cancer cells enhances the sensitivity to aromatase inhibitor (AI) treatment and reverts AI resistance. In murine models, the IC50 of BBT594 on JAK2 inhibition varies between 8nM - 29nM, depending on the cell model and abundant JAK2 mutations.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
569.6
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
882405-89-2
分子式:
C28H30F3N7O3
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