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折扣/货期| 货号：SYN-1226-M001 | 规格：1 mg | 目录价：￥2870 |
| 货号：SYN-1226-M005 | 规格：5 mg | 目录价：￥5894 |
| 货号：SYN-1226-M010 | 规格：10 mg | 目录价：￥9828 |
| 货号：SYN-1226-M050 | 规格：50 mg | 目录价：￥询价 |
| 货号：SYN-1226-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BGG463
别名:
BGG-463
产品描述:
BGG463 (NVP-BGG463) was generated by a rational ‘hybrid design’ approach. Like Imatinib, BGG463 disrupts the assembly of the hydrophobic spine, a characteristic feature of the active state of several kinases, thereby locking the kinase in an inactive ‘DFG-out’ conformation. BGG463 can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 µM, 0.09 µM and 0.590 µM, respectively.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
578.6
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
890129-26-7
分子式:
C30H29F3N6O3
溶解度:
Soluble in DMSO.
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