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折扣/货期| 货号：AG-CP3-7005-M005 | 规格：5 mg | 目录价：￥540 |
| 货号：AG-CP3-7005-M025 | 规格：25 mg | 目录价：￥2160 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Bestatin . hydrochloride
别名:
Ubenimex; NK421; NSC265489; N-(3R-Amino-2S-hydroxy-1-oxo-4-phenylbutyl)-L-leucine
产品描述:
Antibiotic. Potent, competitive and specific aminopeptidase inhibitor. Can be administered in vitro to cultured cells or in vivo with low toxicity. Inhibits aminopeptidase B, aminopeptidase N, leucine aminopeptidase and the aminopeptidase activity of leukotriene A4 (LTA4) hydrolase. It is selective for these aminopeptidases over aminopeptidase A, trypsin, chymotrypsin, elastase, papain, pepsin and thermolysin. Immunomodulator. Displays immunostimulant activity via activation of macrophages and T lymphocytes. Displays anticancer and anti-inflammatory activity. Shown to inhibit proliferation, migration and invasion, and induces autophagy and apoptosis in cancer cells. Inhibits the production of LTB4 in erythrocytes. Has been used as useful tool to assess the physiological role of certain mammalian exopeptidases in the regulation of the immune system, the growth of tumors and their invasion of surrounding tissues and the degradation of cellular proteins.
宿主来源:
Synthetic. Originally isolated from S. olivoreticuli.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
308.4 . 36.5
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
65391-42-6
分子式:
C16H24N2O4 . HCl
溶解度:
Soluble in DMSO (10mg/ml), water (10mg/ml) or methanol (5mg/ml).
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