| 货号:CDX-B0305-G001 | 规格:1 g | 目录价:¥2100 |
| 货号:CDX-B0305-GG25 | 规格:2.5 g | 目录价:¥4200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Bicalutamide
别名:
ICI 176334; ZD 176334; Casodex; Cosudex; N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
产品描述:
Bicalutamide is a potent, non-steroidal anti-androgen that functions as a selective androgen receptor (AR) antagonist, widely used in prostate cancer research and studies involving androgen signaling. It binds competitively to the androgen receptor with high affinity, blocking the action of endogenous androgens such as testosterone and dihydrotestosterone, effectively suppressing androgen-driven cellular processes. Bicalutamide is active in both in vitro and in vivo models and demonstrates good oral bioavailability and metabolic stability. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
430.37
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
90357-06-5
分子式:
C18H14F4N2O4S
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