CD25 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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CD25 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-459

规格：0.1 mg

目录价：￥9038.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD25 Recombinant Protein

别名:

IL2RA, CD25, p55, IL2-RA, IL-2-RA

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.

纯度:

>95% as determined by SDS-PAGE.

生物活性:

Immobilized Human IL-2, Tag Free at 5ug/mL (100 uL/well) can bind Human IL-2 R alpha, His Tag with a linear range of 0.01-1.11 ug/mL.

Accession #:

NP_000408

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