Chenodeoxycholic acid-其他小分子化合物-深圳欣博盛生物科技有限公司

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Chenodeoxycholic acid

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0410-M100	规格：100 mg	目录价：￥240
货号：AG-CN2-0410-M500	规格：500 mg	目录价：￥720

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Chenodeoxycholic acid

别名:

CDCA; Ulmenide; Kebilis; Hekbilin; Fluibil; Chenodiol; Anthropodeoxycholic acid

产品描述:

Cytotoxic hydrophobic primary bile acid [1]. Activator of farnesoid X receptor (FXR), a nuclear receptor that is hepatoprotective and regulates bile acid synthesis (cholesterol 7alpha-hydroxylase (CYP7A1) suppression), conjugation and transport, as well as genes involved in lipid and glucose metabolism and [4-6, 14]. Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, insulin resistance, hyperlipidemia and atherosclerosis [1, 8, 9, 12]. Inhibitor of 5beta-reductase (AKR1D1) [10, 15]. Potent selective inhibitor of DD2 (AKR1C2) [3]. Potent inhibitor of 11beta-HSD1 dehydrogenase [7]. Changes tumor cell viability via IL-6 pathway [11]. Anticancer compound. Apoptosis inducer [13]. Immunosuppressive and anti-inflammatory compound. Modulates oxidative stress [2, 16]. Differentiation regulator of mouse embryonic stem cells [17]. Used for dissolution of cholesterol gallstones.

宿主来源:

Synthetic. Originally isolated from bile.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

392.6

产品形式:

solid

产地:

瑞士