Ursodeoxycholic acid-其他小分子化合物-深圳欣博盛生物科技有限公司

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Ursodeoxycholic acid

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0411-G001	规格：1 g	目录价：￥480
货号：AG-CN2-0411-G005	规格：5 g	目录价：￥1440

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Ursodeoxycholic acid

别名:

UDCA; USAN; BRN 3219888; NSC 657950; NSC 683769

产品描述:

Endogenous hydrophilic bile acid. Antioxidant. Cytoprotective against oxidative stress and cell death. Hepatoprotective at cellular and molecular level, including stabilization of membranes. Protects hepatocytes against bile acid-induced apoptosis. Antiapoptotic and antinecrotic. Targets the mitochondrial function and integrity, reduction of endoplasmatic stress and interactions with survival signals in cAMP, Akt, NF-kappaB, MAPK and PI3K signaling pathways. Modulator and finetuner of the p53-Mdm-2 complex. Chemopreventive against colorectal cancer by countering the tumor-promoting effects of secondary bile acids. Shows also effects on epidermal growth factor receptor (EGFR) signaling and COX-2 expression. Immunomodulator and anti-inflammatory compound. Modifies TLR4 and TLR9 signaling pathways and downregulates the production of proinflammatory tumor necrosis factor-alpha (TNF-alpha). Pregnane X receptor agonist. Neuroprotective. Inhibits neuronal apoptosis. Glucocorticoid Receptor (GR) agonist. Anticholestatic agent. Used to reduce cholesterol absorption and for cholesterol gallstone dissolution. Used to treat primary biliary cirrhosis (PBC). Interferes with the progression of non-alcoholic fatty liver disease (NAFLD)/NASH. Reduces CXCR3 expression [11]. TIMP-1 inducer [12]. ADAM17 inhibitor [12].

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

392.6

产品形式:

solid

产地:

瑞士