Choline Acetyltransferase Antibody: RPE-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

Choline Acetyltransferase Antibody: RPE

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-706D-RPE

规格：100 µg

目录价：￥4901.4

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Choline Acetyltransferase Antibody: RPE

别名:

CHAT_Human Antibody, Acetyl CoA choline O Acetyltransferase Antibody, Choline Acetylase Antibody, CLAT_Human Antibody, CMS1A Antibody

产品描述:

Rabbit Anti-Human Choline Acetyltransferase Polyclonal

反应种属:

Human | Mouse

宿主来源:

Rabbit

实验应用:

WB | ICC/IF

靶标/特异性:

Predicted molecular weight at ~82.5kDa. Observed molecular weights between 68-70kDa.

推荐稀释度:

WB (1:1000); ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Synthetic peptide from the N-terminal to the mid-protein of human Choline O-Acetyltrasferase

免疫原种属:

Human

克隆性:

Polyclonal

纯化方式:

Peptide Affinity Purified

偶联:

RPE

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

Acetylcholine (ACh) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransferase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-choline acetyltransferase a useful specific marker. ChAT is a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease and Down syndrome (1-3).

Accession #:

NP_001136401.1