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折扣/货期| 货号：BVT-0480-C250 | 规格：250 ug | 目录价：￥1920 |
| 货号：BVT-0480-M001 | 规格：1 mg | 目录价：￥5760 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Collinolactone
别名:
Rhizolutin
产品描述:
Collinolactone has neuroprotective and anti-neurodegenerative effects by reducing intracellular oxidative stress. It protects against glutamate-induced oxidative stress in a dose-dependent manner. Collinolactone is a potential anti-Alzheimer agent with Aβ-disaggregating activity. It showed dissociative effect on Aβ aggregates and tau tangles in vitro, with significantly reduced apoptosis and inflammation in neuronal and glial cells. In vivo studies on APP/PS1 double transgenic mice showed substantially dissociated hippocampal plaques. A set of semisynthetic collinolactone analogs (but not collinolactone) has shown inhibitory effects on a L929 cell line.
宿主来源:
Isolated from Streptomyces sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
360.45
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
2733581-46-7
分子式:
C21H28O5
溶解度:
Soluble in DMSO, pyridine, toluene, benzene or acetonitrile. Insoluble in water. We recommend to avoid solutions in methanol. Protect from pH-values below pH 4.0 and above pH 8.0.
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