深圳欣博盛生物科技有限公司 a1

Seriniquinone
货号:BVT-0478-M001 规格:1 mg 目录价:¥720
货号:BVT-0478-M005 规格:5 mg 目录价:¥2160
货号:BVT-0478-M010 规格:10 mg 目录价:¥3840
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Seriniquinone
别名:
Dinaphtho[2,3-b:2',3'-d]thiophene-5,7,12,13(5aH,12bH)-tetraone
产品描述:
Seriniquinone is a potent cytotoxic and melanoma-selective anticancer agent. Upon cellular treatment and based on the compounds fluorescent nature it was found localized in the endoplasmic reticulum. Seriniquinone inhibits cell proliferation marked by autophagocytosis and induces cell death due to caspase-9 dependent apoptosis. Mode of action studies suggest that it specifically targets a skin protective antimicrobial peptide dermcidin (DCD), whose role as a cancer-protective protein has been recently recognized.
宿主来源:
Synthetic. Originally isolated from marine bacterium Serinicoccus sp. strain CNJ927.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
344.3
产品形式:
solid
有效期:
Stable for at least 1 year after receipt when stored at -20°C.Stock solutions are stable for at least 3 months when stored at -20°C.
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
22200-69-7
分子式:
C20H8O4S
溶解度:
Soluble in DMSO (10mg/ml) or DMF (15mg/ml). Insoluble in water.
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