Copper Transporting ATPase 2 Antibody: ATTO 488-单抗-深圳欣博盛生物科技有限公司

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Copper Transporting ATPase 2 Antibody: ATTO 488

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-399D-A488

规格：100 µg

目录价：￥4926.6

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Copper Transporting ATPase 2 Antibody: ATTO 488

别名:

ATP7B Antibody, ATPase Cu++ transporting beta polypeptide Antibody, ATPase Cu(2+) transporting beta polypeptide Antibody, Copper pump 2 Antibody, Copper transporting ATPase 2 Antibody, PWD Antibody, Toxic milk Antibody, tx Antibody, WC1 Antibody, WD Antibody, Wilson disease associated protein Antibody, WND Antibody, WND/140 kDa Antibody

产品描述:

Mouse Anti-Human Copper Transporting ATPase 2 Monoclonal IgG1

反应种属:

Human | Mouse | Rat

宿主来源:

Mouse

实验应用:

WB | IHC | ICC/IF | IP

靶标/特异性:

Detects ~160kDa in rat brain membrane preparations.

同种型:

IgG1

推荐稀释度:

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

L62/29 (Formerly sold as S62-29)

纯化方式:

Protein G Purified

偶联:

ATTO 488

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage.

Accession #:

NP_000044.2