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折扣/货期| 货号：SIH-324-125MG | 规格：125 mg | 目录价：￥2203.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DMPO
别名:
2,2-Dimethyl-3,4-dihydro-2H-pyrrole 1-oxide, 5,5-Dimethyl-1-Pyrroline-N-Oxide, 3,4-dihydro-2,3-dimethyl-2H-pyrrole 1-oxide
产品描述:
Spin trapping reagent
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
113.16
产品形式:
Liquid
产地:
加拿大
功能与背景:
The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states (1). The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems (2-6). Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals (1). DMPO adducts can be generated with protein and DNA radicals (7).
纯度:
>98%
来源:
Synthetic
CAS号:
3317-61-1
分子式:
C6H11NO
溶解度:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
PubChem CID:
1774
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