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折扣/货期| 货号：96-864 | 规格：0.1 mg | 目录价：￥8126 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DNAM-1 Recombinant Protein
别名:
DNAM1,CD226,PTA1
实验应用:
ELISA,WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Tris with Glycine, Arginine and NaCl, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
纯度:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
生物活性:
Measured by its binding ability in a functional ELISA. Immobilized Human DNAM-1, Fc Tag at 10 ug/mL (100 ul/well),can bind Human Nectin-2, His Tag with a linear range of 0.08-1.25 ug/mL.
Accession #:
NP_006557
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