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折扣/货期| 货号：SIH-390-10MG | 规格：10 mg | 目录价：￥1900.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Doxorubicin Hydrochloride
别名:
Adriamycin
产品描述:
Apoptosis Inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
580
产品形式:
Red-Orange powder
产地:
加拿大
功能与背景:
Doxorubicin Hydrochloride is used in a clinical setting for the treatment of a wide range of cancers, including lymphomas, leukemias, and solid tumors of the breast, pancreas, stomach, bladder, and ovaries. This drug intercalates into DNA and therefore induces apoptosis by hindering cellular functions like replication and transcription by specifically inhibiting the binding of reverse transcriptase, RNA polymerase and topoisomerase II. Doxorubicin has some adverse effects for patients including immunosuppressive effects caused by hematologic toxicity. Doxorubicin has also been shown to induce autophagy in a species-specific manner.
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
25316-40-9
分子式:
C27H29NO11•HCl
溶解度:
May be dissolved in water (25 mg/ml); or DMSO (30 mg/ml)
PubChem CID:
443939
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