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折扣/货期| 货号：AG-CR1-3505-G001 | 规格：1 g | 目录价：￥13800 |
| 货号：AG-CR1-3505-M025 | 规格：25 mg | 目录价：￥660 |
| 货号：AG-CR1-3505-M100 | 规格：100 mg | 目录价：￥1980 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ds(+)-threo-Isocitric acid . trisodium salt
别名:
(1R,2S)-1-Hydroxy-1,2,3-propanetricarboxylic acid; (2R,3S)-Isocitric acid . trisodium salt
产品描述:
Anticoagulant that retains platelets functionality. Buffers Ca2+ activity in physiological range (~1mM). Bypasses the metabolic blockade, may permit heme biosynthesis but does not suffice to reverse the iron-restriction response. Stabilizes the iron-sulfur cluster and is predicted to restore aconitase to its 'high iron' conformation and thereby dissociates the PKC-associated signaling complexes whose hyperactivation impairs Epo responsiveness. Binds IDH (isocitrate dehydrogenase), an excellent candidate for participating, along with aconitase and PKC, in an iron restriction signalosome. Contributes to heme biosynthesis which may account for its greater potency in restoring erythroid differentiation.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
189.1 . 69.0
产品形式:
solid
纯度:
>98% (NMR)
CAS号:
903507-52-8
分子式:
C6H5O7 . 3Na
促销活动
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