Famotidine-其他小分子化合物-深圳欣博盛生物科技有限公司

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Famotidine

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3730-G001	规格：1 g	目录价：￥360
货号：AG-CR1-3730-G005	规格：5 g	目录价：￥1080

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Famotidine

别名:

MK-208; YM-11170; Pepcid; N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine

产品描述:

Famotidine is a histamine H2 receptor antagonist. It is selective for H2 over H1 and muscarinic receptors (Kis = 4 and 28 µM, respectively, in bovine cerebral cortex). Famotidine blocks the action of histamine in the parietal cells, ultimately blocking acid secretion in the stomach. It inhibits histamine-induced acid secretion in isolated canine parietal cells (IC50 = 0.6µM) and suppresses histamine-induced gastric acid secretion in dogs when administered orally and in anesthetized rats when administered intraduodenally (ID50s = 10 and 400µg/kg, respectively). Famotidine is used to treat ulcers, gastroesophageal reflux disease (GERD) and heartburn and it decreases the risk of gastrointestinal toxicity associated with non-steroidal anti-inflammatory drugs (NSAIDs). Potential inhibitor of the viral enzyme papain-like protease (PLpro), important for SARS-CoV-2 replication and being tested in COVID-19 clinical trials.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

337.5

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)