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折扣/货期| 货号：AG-CN2-0057-C010 | 规格：10 ug | 目录价：￥2280 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Fostriecin
别名:
Phosphotrienin; CI-920; CL-1565A; NSC-339638; PD 110,161; Pyranone phosphate
产品描述:
Antibiotic [1, 2, 18]. Anticancer compound [1-5, 8, 9, 11]. Antifungal [6]. Catalytic inhibitor of topoisomerase II (IC50 = 40 µM) [7, 16]. Potent protein phosphatase 2A (PP2A) (IC50 = 1.5 nM) and 4 (PP4) (IC50 = 3 nM) inhibitor [10, 12, 15]. Weak protein phosphatase type 1 (PP1) inhibitor (IC50=131µM). No apparent inhibition on PP2B [10, 12]. Mitotic entry checkpoint inhibitor [10]. Mediates cell cycle arrest at G2-M-phase [14]. Ischemia protective [13]. The PP2A binding site is different from that of okadaic acid [17, 19]
宿主来源:
Isolated from Streptomyces pulveraceous.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
452.4
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
87860-39-7
分子式:
C19H26O9PNa
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