| 货号:33-586 | 规格:100 ug | 目录价:¥10986.3 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Gamma Catenin Antibody [15F11]
别名:
Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
反应种属:
Human,Mouse,Rat,Cat,Dog,Chicken,Bovine
宿主来源:
Mouse
实验应用:
IF,WB,IP
同种型:
IgG1, kappa
克隆性:
Monoclonal
克隆号:
15F11
纯化方式:
Protein G affinity chromatography
偶联:
Unconjugated
产品浓度:
0.2 mg/mL
保存温度:
Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
产地:
美国
生产商:
Prosci
功能与背景:
Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]
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