| 货号:AG-CN2-0427-M010 | 规格:10 mg | 目录价:¥300 |
| 货号:AG-CN2-0427-M050 | 规格:50 mg | 目录价:¥420 |
| 货号:AG-CN2-0427-M250 | 规格:250 mg | 目录价:¥840 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Genistein
别名:
NSC 36586; Baichanin A; Differenol A; 4',5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
产品描述:
Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades [1]. Inhibitor of mammalian DNA topoisomerase II [2]. Anticancer agent, inducing cell cycle arrest and apoptosis [3]. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis [12]. Binds estrogen receptor beta. Can increase the rate of growth of some ER expressing breast cancers [4, 10]. Potent alpha-glucosidase inhibitor [5]. Anthelmintic [6]. Anti-diabetic. Activates nuclear receptors, oestrogen receptors and peroxisome proliferator-activated receptors (all PPAR isoforms) and it inhibits various enzyme activities [7, 8, 14]. Inhibitor of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes [9]. Stimulator of autophagy vacuolization [12]. Antioxidant [13]. TRAIL sensitizer [15]. Acts as an agonist at the GPR30 receptor [16]. MALT1 inhibitor [17] DNA methyltransferase inhibitor [18]. Genistein exhibits synergistic antibacterial effects on MRSA [19].
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
270.2
产品形式:
solid
产地:
瑞士
纯度:
>99%
CAS号:
446-72-0
分子式:
C15H10O5
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