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折扣/货期| 货号：AG-CN2-0426-G001 | 规格：1 g | 目录价：￥240 |
| 货号：AG-CN2-0426-G005 | 规格：5 g | 目录价：￥720 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Itaconic acid [Itaconate]
别名:
Itaconate; Methylenesuccinic acid; 2-Propene-1,2-dicarboxylic acid
产品描述:
Mammalian antibacterial metabolite. Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth [1, 4]. Antimicrobial. Antibacterial [1, 3, 4]. Inhibits the growth of bacteria expressing isocitrate lyase [1, 3, 4]. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat [2]. Might be involved in the regulation of metabolism [2]. One of the most highly induced metabolites in activated macrophages. Exerts anti-inflammatory effects in vitro and in vivo. Regulates succinate levels by inhibiting succinate dehydrogenase (SDH). Regulates mitochondrial respiration and cytokine production. Might induce inflammasome activation and consequently IL-1beta secretion by generating ROS.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
130.1
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>99%
CAS号:
97-65-4
分子式:
C5H6O4
溶解度:
Soluble in water, ethanol or methanol.
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