官网链接
折扣/货期| 货号：SYN-1114-M001 | 规格：1 mg | 目录价：￥2870 |
| 货号：SYN-1114-M005 | 规格：5 mg | 目录价：￥5824 |
| 货号：SYN-1114-M010 | 规格：10 mg | 目录价：￥8162 |
| 货号：SYN-1114-M050 | 规格：50 mg | 目录价：￥询价 |
| 货号：SYN-1114-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GNE-490
别名:
GNE490
产品描述:
GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR. It has good pharmacokinetic (PK) parameters and demonstrates knock down of pathway markers in vivo. Originally obtained via modification of compounds like GDC-0941, GNE-490 which have a significantly reduced potency mTOR while maintaining effective potency for PI3K substrates. IC(50) values for PI3K family members are in the subnanomolar to low nanomolar range (-.28 to < 20nm) while IC(50) values for mTOR and other related tyrosine kinases are greater than 750nM with most being greater than 1µM or more, thus GNE-490 makes a good choice for examining PI3K related events separate from those mediated by mTOR.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
386.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1033739-92-2
分子式:
C18H22N6O2S
促销活动
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