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折扣/货期| 货号：CDX-G0069-M250 | 规格：250 mg | 目录价：￥2226 |
| 货号：CDX-G0069-G001 | 规格：1 g | 目录价：￥6664 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Guanosine 5'-triphosphate sodium salt hydrate
别名:
GTP; 5'-GTP Salt
产品描述:
Guanosine 5'-triphosphate (GTP) trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. GTP is involved in the initiation of peptide synthesis during the binding of formylmethionyl-tRNA (F-met-tRNA) to the ribosome. It is also involved in polypeptide chain elongation. GTP is hydrolyzed by tubulin and its hydrolysis is accompanied by microtubule assembly. Guanosine 5'-triphosphate trisodium salt up-regulates miRNA (specifically miR133a and miR133b) and myogenic regulator factor and induces human myogenic precursor cells to release exosomes stuffed with guanosine based molecules (mainly guanosine) in the extracellular milieu.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
523.18 (free acid basis)
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>97% (NMR)
CAS号:
36051-31-7
分子式:
C10H16N5O14P3 . xNa+
溶解度:
Soluble in water (50mg/ml).
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