深圳欣博盛生物科技有限公司 a1

Hemagglutinin Recombinant Protein
品牌:ProSci LLC
货号:95-101 规格:0.05 mg 目录价:¥4226.625
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Hemagglutinin Recombinant Protein
别名:
H5N1 Hemagglutinin HA1, H5N1 Hemagglutinin, H5N1 HA1, HA1
实验应用:
ELISA,WB
表达系统:
E. coli
保存温度:
Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
1X PBS containing 0.1% SDS and 0.02% NaN3
产地:
美国
生产商:
Prosci
功能与背景:
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, but it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with host cell surface proteins containing oligosaccharides with terminal sialyl residues. Its extracellular region has two domains (HA1 and HA2); HA1 is cleaved from the main hemagglutinin protein by the host immune system. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong (3). This more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the efficiency of this type of transmission is low (4). Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability (5). This HA1 recombinant protein is recognized by several ProSci hemagglutinin antibodies.
纯度:
~95%
Accession #:
AAT76166
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