PUMA Fragment Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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PUMA Fragment Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：95-102

规格：0.05 mg

目录价：￥4226.625

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PUMA Fragment Recombinant Protein

别名:

PUMA Antibody : JFY1, PUMA, JFY-1

实验应用:

ELISA,WB

表达系统:

E. coli

保存温度:

Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

1X PBS containing 0.1% SDS and 0.02% NaN₃

产地:

美国

生产商:

Prosci

功能与背景:

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse (1-3). PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA- and PUMA- (1). PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. This PUMA recombinant protein is recognized by several ProSci PUMA monoclonal antibodies, but not the two polyclonal antibodies (PSI # 3041 and 3043).

纯度:

~95%

Accession #:

Q9BXH1

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