Human Recombinant Alpha Synuclein Pre-formed Fibrils phosphorylated at position 129-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human Recombinant Alpha Synuclein Pre-formed Fibrils phosphorylated at position 129

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPR-521XE

规格：500 µg (@5mg/ml)

目录价：￥36792

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human Recombinant Alpha Synuclein Pre-formed Fibrils phosphorylated at position 129

别名:

Alpha synuclein, Alpha-synuclein pre-formed fibril, Alpha synuclein protein PFF, Alpha synuclein PFF, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, SYN protein, Parkinson disease familial 1 Protein

产品描述:

Human Recombinant Alpha Synuclein pSer129 Pre-formed Fibrils

反应种属:

Human

实验应用:

WB | SDS-PAGE | In vivo assay | In vitro assay

纯化方式:

Ion-exchange Purified

偶联:

No Tag

产品浓度:

2 mg/ml or 5 mg/ml

表达系统:

E. coli

保存温度:

-80ºC

运输温度:

Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

预期分子量:

14.46 kDa

存储溶液:

PBS pH 7.4

产地:

加拿大

功能与背景:

Serine 129 is the C-terminal serine characteristic to mammalian alpha synuclein, with this serine being determined to be a major phosphorylation site (1). Lewy Bodies in Parkinson’s Disease (PD) and other related synucleinopathies are comprised of alpha synuclein phosphorylated at serine 129 and this phosphorylation may contribute to an increased propensity to aggregate (2). Due to phosphorylation at serine 129 being one of the most abundant PTMs, several studies reported on the PTM as a potential biomarker (3). Our Alpha Synuclein Ser129 Pre-Formed Fibrils are generated in-vitro from purified phosphorylated monomer and phosphorylation is confirmed with our anti-ASYN pS129 monoclonal antibody (Catalog# SMC-600).

纯度:

>95%