Inosine-其他小分子化合物-深圳欣博盛生物科技有限公司

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Inosine

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-3554-G001	规格：1 g	目录价：￥720
货号：AG-CR1-3554-M100	规格：100 mg	目录价：￥240
货号：AG-CR1-3554-M500	规格：500 mg	目录价：￥420

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Inosine

别名:

9-beta-D-Ribofuranosylhypoxanthine; NSC 20262; Hypoxanthine 9-beta-D-ribofuranoside

产品描述:

Inosine, an intermediate in purine metabolism, consists of hypoxanthine and ribose. It is an inert purine nucleoside formed by breakdown of adenosine (deamination, known as A-to-I editing that occurs in tRNA and mRNA) or also is generated by the action of 5'-nucleotidase on inosine monophosphate (IMP). Inosine has neuroprotective, cardioprotective, immunomodulatory, anti-tumor and anti-inflammatory effects in different experimental models. Inosine functions are mediated in receptor-dependent or-independent manners. The receptor-mediated function of inosine is thought to be related to adenosine receptor family members including A1, A2A, A2B, and A3 G-protein coupled receptors. It is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors. Inosine is released from brown adipocytes (BAs) upon stress. Inosine activates purinergic P1 receptors, triggering BA activation and white adipocyte browning. Consequently, inosine increases whole-body energy consumption and alleviates diet-induced obesity in mice. Inosine and other closely related purines might be a novel approach to tackle obesity and associated metabolic disorders by enhancing energy expenditure. Inosine is a potent activator of brown adipose tissue and energy homeostasis.

宿主来源:

Synthetic.

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

268.2

产品形式:

solid

产地:

瑞士