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折扣/货期| 货号：AG-CN2-0418-M001 | 规格：1 mg | 目录价：￥780 |
| 货号：AG-CN2-0418-M005 | 规格：5 mg | 目录价：￥1920 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ionomycin . calcium salt
别名:
Antibiotic SQ 23377; EM 94
产品描述:
Antibiotic [1]. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators [2, 3]. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+ [3, 9]. Apoptosis inducer [4, 7]. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination [6]. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA [5, 8]. ADAM10 agonist [10]. Potent inducer of shedding CXCL16 [10]. TREK-1 channels inhibitor [11]. PPARgamma ligand with a unique binding mode. Shows effective glucose-lowering activity in a mouse model of diabetes [12].
宿主来源:
Isolated from Streptomyces conglobatus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
707.0 . 40.1
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC, TLC)
CAS号:
56092-82-1
分子式:
C41H70O9 . Ca
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