Ionomycin . calcium salt-其他小分子化合物-深圳欣博盛生物科技有限公司

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Ionomycin . calcium salt

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0418-M001	规格：1 mg	目录价：￥780
货号：AG-CN2-0418-M005	规格：5 mg	目录价：￥1920

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Ionomycin . calcium salt

别名:

Antibiotic SQ 23377; EM 94

产品描述:

Antibiotic [1]. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators [2, 3]. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+ [3, 9]. Apoptosis inducer [4, 7]. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination [6]. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA [5, 8]. ADAM10 agonist [10]. Potent inducer of shedding CXCL16 [10]. TREK-1 channels inhibitor [11]. PPARgamma ligand with a unique binding mode. Shows effective glucose-lowering activity in a mouse model of diabetes [12].

宿主来源:

Isolated from Streptomyces conglobatus.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

707.0 . 40.1

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.