Mycophenolic acid-其他小分子化合物-深圳欣博盛生物科技有限公司

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Mycophenolic acid

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0419-M100	规格：100 mg	目录价：￥840
货号：AG-CN2-0419-M500	规格：500 mg	目录价：￥3360

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Mycophenolic acid

别名:

MPA; NSC 129185; Ly 68618; Mycophenolate

产品描述:

Antibiotic [1]. Shows antiviral, antifungal and antitumor properties [1, 2]. Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis [3-6, 13]. Potent reversible inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), leading to depletion of GMP and interruption of the de novo synthesis of purine nucleotides necessary for B and T lymphocyte proliferation [7, 8]. Inhibits the type II IMPDH isoform (IMPDH-2) 5-fold more potently compared to type I isoform [11]. Inhibits RNA and DNA synthesis [13]. Inducible nitric oxide synthase (iNOS/NOS II) inhibitor [8, 10]. Apoptosis and necrosis inducer [9, 12]. Novel type of inhibitor against RNA guanylyltransferases [14]. Inhibits TNF-alpha-stimulated MAPK/NF-kappaB and ROS generation [15]. Autophagy suppressor. Broad-spectrum antiviral compound with inhibitory activity against different coronavirus, including SARS-CoV, MERS-CoV and SARS-CoV-2, cause of COVID-19. It binds to the active site of SARS-CoV-2 papain-like protease (PLpro) possibly inhibiting viral replication.

宿主来源:

Isolated from Penicillium brevi-compactum.

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

320.3

产品形式:

solid

产地:

瑞士