IRAK Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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IRAK Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：95-112

规格：0.05 mg

目录价：￥4226.625

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IRAK Recombinant Protein

别名:

IRAK Antibody: IRAK, pelle, IRAK, Interleukin-1 receptor-associated kinase 1, IRAK-1

实验应用:

ELISA,WB

表达系统:

E. coli

保存温度:

Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

100mM sodium phosphate, 500mM NaCl, 25 mM imidazole, 10% gycerol

产地:

美国

生产商:

Prosci

功能与背景:

Nuclear factor kappa B (NF-B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently (1,2). IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response (3). IRAK mediates a signaling cascade leading to NF-B activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF) (1,4).

纯度:

~95%

Accession #:

P51617

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