Irbesartan-其他小分子化合物-深圳欣博盛生物科技有限公司

首页产品中心其他小分子化合物

Irbesartan

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-I0204-M050	规格：50 mg	目录价：￥1470
货号：CDX-I0204-M250	规格：250 mg	目录价：￥5894

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Irbesartan

别名:

2-Butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one; Avapro; BMS-186295; SR-47436

产品描述:

Irbesartan is an orally available angiotensin II type 1 (AT1) receptor antagonist (IC50 = 1.3 nM) with antihypertensive activity. It binds to AT1 receptor with >5000 times higher affinity compared to AT2 receptor. Irbesartan also elicits selective peroxisome proliferator-activated receptor gamma (PPARgamma)-modulating activity and exhibits metabolic, anti-inflammatory and antioxidative properties. Irbesartan inhibits the receptor for advanced glycation end-products (RAGE)/high mobility group box 1 (HMGB1) axis and maybe useful in prevention and treatment of various diseases. Formulations containing irbesartan have been used, alone and in combination with diuretics, in the treatment of hypertension.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

428.5

产品形式:

solid

产地:

瑞士