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折扣/货期| 货号：SIH-243-250MG | 规格：250 mg | 目录价：￥6091.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Irinotecan HCl
别名:
(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate, CPT11, Camptothecin 11
产品描述:
Topoisomerase I inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
623.14
产品形式:
Yellow solid
产地:
加拿大
功能与背景:
Irinotecan is a topoisomerase 1 inhibitor, which prevents DNA from unwinding. Chemically it is a semisynthetic analogue of the natural alkaloid camptothecin. It is activated by hydrolysis to SN-38 which is then inactivated by glucuronidation by UGT1A1. This inactivation eventually leads to inhibition of both DNA replication and transcription (1, 2).
纯度:
>98%
来源:
Synthetic
CAS号:
100286-90-6
分子式:
C33H38N4O6•HCl
溶解度:
Soluble to 50 mg/ml in DMSO
PubChem CID:
74990
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