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折扣/货期| 货号：CDX-J0010-L001 | 规格：1 ml | 目录价：￥1106 |
| 货号：CDX-J0010-L005 | 规格：5 ml | 目录价：￥3304 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Josamycin Solution (in acetonitrile)
别名:
Kitasamycin A3; Leucomycin A3; Turimycin A5
产品描述:
Josamycin is a member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. It is an antimicrobial against a wide variety of pathogens. It has activity against Gram-positive an Gram-negative bacteria. The mechanism of action is via inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, inhibiting peptidyltransferase and ribosomal translocation, thereby inhibiting translocation of peptidyl tRNA. Josamycin may overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein (Pgp). It is used to study the modification of phagocytosis and cytokine production by macrolide antibiotics and immunomodulatory effects.
宿主来源:
Microbial
产品浓度:
10µg/ml in acetonitrile
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
827.99
产品形式:
liquid
产地:
瑞士
纯度:
>98% (UV)
CAS号:
16846-24-5
分子式:
C42H69NO15
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